
ACC foes match up when the No. 14 Louisville Cardinals (7-1) and the California Golden Bears (5-4) square off on Saturday, November 8, 2025 at L&N Federal Credit Union Stadium.
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Louisville vs. Cal Matchup Info
- Game date: Saturday, November 8, 2025
- Game time: 7 p.m. ET
- Location: Louisville, Kentucky
- Venue: L&N Federal Credit Union Stadium
- TV channel: ESPN2
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Louisville vs. Cal Odds and Prediction
- Spread favorite: Cardinals (-18.5)
- Moneyline: Cardinals (-1053), Golden Bears (+680)
- Total: 49.5 points
- Pick ATS: Louisville (-18.5)
- Pick OU: Over (49.5)
- Prediction: Louisville 37, Cal 15
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Louisville vs. Cal Betting Records and Insights
- Louisville is 3-5-0 ATS this season.
- Cal has covered three times in nine chances against the spread this year.
- The Cardinals have been favored by 18.5 points or more this season three times and failed to cover in all three.
- Louisville and its opponent have combined to go over the point total four out of eight times this season.
- So far this year, four of Cal's nine games with a set number have hit the over.