Warriors vs. Lakers Predictions, Odds & Stats – Oct. 21

Los Angeles Lakers v Phoenix Suns

Photo: Kelsey Grant / Getty Images Sport / Getty Images

In the 2025-26 season opener for both teams, the Golden State Warriors are favored by 2.5 points against the Los Angeles Lakers on Tuesday, October 21, 2025 at 10 p.m. ET. The matchup airs on NBC/Peacock.

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Warriors vs. Lakers Predictions for Tuesday

Our computer projections model for this game predicts a final score of Lakers 112, Warriors 111.

  • Moneyline Pick: Lakers (+121)
  • Total Pick: Under 227.5 (computer predicts 223.5 points)
  • Pick ATS: Lakers (+2.5)

Recent Warriors vs. Lakers Matchups

Warriors vs Lakers (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
4/3/2025 Lakers -1.5 230.5 -114 -105 123-116 GS
2/6/2025 Lakers -6.5 224.5 -260 +210 120-112 LAL
1/25/2025 Lakers -1 218.5 -113 -106 118-108 LAL
12/25/2024 Warriors -3.5 219.5 -164 +139 115-113 LAL

Warriors 2024-25 Betting Trends

  • Golden State's record against the spread last year was 42-40-0.
  • The Warriors went 23-28 as 2.5-point favorites or more last year.
  • Last year, 41 of Golden State's 82 games went over the point total.
  • The Warriors finished with a 37-18 record in games they were listed as the moneyline favorite last season (winning 67.3% of those games).
  • Golden State had a record of 32-18 when it played as a moneyline favorite with odds of -144 or shorter last year (64%).

Lakers 2024-25 Betting Trends

  • Los Angeles covered 45 times in 82 chances against the spread last year.
  • The Lakers' ATS record as underdogs of 2.5 points or greater was 15-14 last year.
  • A total of 41 of Los Angeles' games last year went over the point total.
  • The Lakers were underdogs 33 times last season and won 15, or 45.5%, of those games.
  • Last season, Los Angeles won nine of its 26 games, or 34.6%, when it was the underdog by at least +121 on the moneyline.

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Warriors vs. Lakers Injury Report

Warriors

Warriors:

De'Anthony Melton: Out (Knee),

Moses Moody: Out (Calf),

Alex Toohey: Out (Knee)

Lakers

Lakers:

Maxi Kleber: Out (Oblique),

LeBron James: Out (Nerve)

Warriors vs. Lakers Game Time and TV Channel

  • Game day: Tuesday, October 21, 2025
  • Game time: 10 p.m. ET
  • TV channel: NBC/Peacock
  • Location: Los Angeles, California
  • Arena: Crypto.com Arena
  • Live stream: Watch this game on Fubo (Regional restrictions may apply)

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